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Safety in pregnancy has not been established for cefiximeThere are no adequate studies in pregnant womenhoweverstudies in animals suggest no important effects on the fetus.
Clostridium difficile associated diarrheaCDADhas been reported with use of nearly all antibacterial agentsincluding Supraxand may range in severity from mild diarrhea to fatal colitisTreatment with antibacterial agents alters the normal flora of the colon leading to overgrowth of Cdifficile
Cefixime comes as a tabletchewable tabletcapsuleand suspensionliquidto take by mouthIt is usually taken with or without food every 12 or 24 hoursWhen used for the treatment of gonorrhea it may be given in a single doseTake cefixime at around the same times every dayFollow the directions on your prescription label carefullyand ask your doctor or pharmacist to explain any part you do not understandTake cefixime exactly as directedDo not take more or less of it or take it more often than prescribed by your doctor.
Safety and effectiveness of cefixime in children aged less than six months old have not been establishedThe incidence of gastrointestinal adverse reactionsincluding diarrhea and loose stoolsin the pediatric patients receiving the suspensionwas comparable to the incidence seen in adult patients receiving tablets.
A very serious allergic reaction to this drug is rareHoweverget medical help right away if you notice any symptoms of a serious allergic reactionincludingrashitching/swellingespecially of the face/tongue/throatsevere dizzinesstrouble breathing.
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in a study in pediatric patients 1-24 months of age with urinary tract infections, a 14-day regimen of oral cefixime 16 mg kg on day 1 followed by 8 mg kg once daily was as effective as a 14-day regimen that included a parenteral drug iv cefotaxime 200 mg kg daily given in 4 divided doses for 3 days or until the child is afebrile for 24 hours followed by oral cefixime 8 mg kg once daily .